Dataset Number of interactions Publication Download
HuRI 52570 BioRxiv HuRI
HI-Union 64007 HI-Union
Dataset Number of interactions Download
HI-III 54495 H-III
unpublished GSM test space 2129 unpublished GSM test space
unpublished GS test space 821 unpublished GS test space.
unpublished pilot screen 1338 unpublished_pilot_screen
Dataset Number of interactions Publication Download
HI-II-14 13872 25416956 Rolland et al.(2014)
Yu-11 1181 21516116 Yu et al.(2011)
HI-I-05 2747 16189514 Rual et al.(2005)
Yang-16 726 26871637 Yang et al.(2016)
Venkatesan-09 196 19060904 Venkatesan et al.(2009)
Lit-BM 13030 LitBM-17

Publication Moratorium


All users are expected to observe the following guidelines when using preliminary, unpublished data from the CCSB Human Interactome. This includes the data accompanying our recently posted reference interactome manuscript on the BioRxiv:

·       Registered users may download and analyze all verified or validated datasets.

·       There is a "moratorium" on dissemination of binary interaction screening data or derived results, including publication of global analysis of the data. The moratorium period for released interaction data ends 12 months after the entire verified data set obtained from one complete screen has been made publicly available or immediately upon publication of the corresponding dataset by CCSB (whichever comes first). We grant an exception to this moratorium for dissemination in the form of presentations or publications that are focused around small numbers of interactions, which we define to be either a set of up to 10 interactions, or all of the interactions involving a specific protein, whichever is less restrictive.

·       The moratorium on dissemination is considered to extend to all forms of public disclosure, including meeting abstracts, oral presentations, and formal electronic submissions to publicly accessible sites (e.g., public websites, web blogs).

·       Users are expected to acknowledge the following in all oral or written presentations, disclosures, or publications of the analyses (before or after the moratorium period):

·    The Center for Cancer Systems Biology (CCSB) at the Dana-Farber Cancer Institute

·    The funding organization(s) that supported the work:

o  The National Human Genome Research Institute (NHGRI) of NIH

o  The Ellison Foundation, Boston, MA

o  The Dana-Farber Cancer Institute Strategic Initiative

·    The fact that interactions were verified but not yet validated, where that is the case.


·    The date on which interaction dataset was downloaded, allowing readers the opportunity to efficiently identify which interactions in preliminary datasets might have been subsequently corrected (e.g., due to subsequent failure to validate)